Prominent settings include South Park Elementary, various neighborhoods and the surrounding mountain range, actual Colorado landmarks, and the businesses along the town's main street, all of which are based on the appearance of similar locations in Fairplay, Colorado. The town is also home to an assortment of other characters, including students, families, elementary school staff, and other various residents. The boys live in the fictional small town of South Park, located within the real-life South Park basin in the Rocky Mountains of central Colorado, approximately one hour's drive from Denver. South Park follows centers around four boys: Stan Marsh, Kyle Broflovski, Eric Cartman and Kenny McCormick. In 2013, TV Guide ranked South Park the tenth Greatest TV Cartoon of All Time. A theatrical film, South Park: Bigger, Longer & Uncut, was released in June 1999 to commercial and critical success, garnering an Academy Award nomination.

It has received numerous accolades, including five Primetime Emmy Awards and a Peabody Award.

South Park has received critical acclaim, and is included in various publications' lists of greatest television shows. In August 2021, the series was renewed through 2027, and a series of films was announced for the streaming service Paramount+, the first two of which were released later that year. Subsequent ratings have varied, but it remains one of Comedy Central's highest-rated programs. It debuted with great success, consistently earning the highest ratings of any basic cable program. Since its debut on August 13, 1997, 317 episodes (including television films) of South Park have been broadcast. South Park features a large ensemble cast of recurring characters. The pilot episode was produced using cutout animation subsequent episodes have since used computer animation recalling the cutout technique. The second short became one of the first Internet viral videos, leading to South Park 's production.

Parker and Stone developed South Park from two animated short films both titled The Spirit of Christmas. South Park became infamous for its profanity and dark, surreal humor that satirizes a wide range of topics toward an adult audience. The series revolves around four boys- Stan Marsh, Kyle Broflovski, Eric Cartman, and Kenny McCormick-and their exploits in and around the titular Colorado town. South Park is an American animated sitcom created by Trey Parker and Matt Stone and developed by Brian Graden for Comedy Central.

MTV Entertainment Studios (2021–present).

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